Risk factors for positive or equivocal margins after wide local excision of 1345 cutaneous melanomas
نویسندگان
چکیده
منابع مشابه
Positive Tumor Margins in Wide Local Excision of Breast Cancer: A 10-Year Retrospective Study
Background. The safety of wide local excision as a standard surgical option for early stage breast cancer management in Ghana has not been evaluated. The aim of this study was to use retrospective histopathological descriptive study to evaluate the prevalence of positive tumor margins in wide local excision specimens and offer recommendations. Study design. We reviewed 147 breast lumps, followi...
متن کاملSurgical excision margins for primary cutaneous melanoma.
BACKGROUND Cutaneous melanoma accounts for 75% of skin cancer deaths. Standard treatment is surgical excision with a safety margin some distance from the borders of the primary tumour. The purpose of the safety margin is to remove both the complete primary tumour and any melanoma cells that might have spread into the surrounding skin.Excision margins are important because there could be trade-o...
متن کاملWide versus narrow excision margins for high-risk, primary cutaneous melanomas: long-term follow-up of survival in a randomised trial
BACKGROUND The necessary margin of excision for cutaneous melanomas greater than 2 mm in thickness is controversial. At a median follow-up of 5 years, findings from our previously published randomised trial of narrow (1 cm) versus wide (3 cm) excision margins in patients with thick cutaneous melanomas showed that narrow margins were associated with an increased frequency of locoregional relapse...
متن کاملEffect of margins of excision on recurrence after local excision of ductal carcinoma in situ of the breast.
AIMS To determine important factors influencing recurrence after local excision of duct carcinoma in situ (DCIS) of the breast. MATERIALS AND METHODS The extent (size) in millimetres, classification (by cytonuclear grade (NHSBSP system), by extent of necrosis, and by the Van Nuys system), and excision margins of 115 cases of screen detected DCIS treated by local excision were measured. A prog...
متن کاملResidual disease after re-excision lumpectomy for close margins.
INTRODUCTION While a positive margin after an attempt at breast conservation therapy (BCT) is a reason for concern, there is more controversy regarding close margins. When re-excisions are performed, there is often no residual disease in the new specimen, calling into question the need for the procedure. We sought to examine the incidence of residual disease after re-excision for close margins ...
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ژورنال
عنوان ژورنال: Journal of the American Academy of Dermatology
سال: 2017
ISSN: 0190-9622
DOI: 10.1016/j.jaad.2017.03.025